Redox proteins are constitutively secreted by skeletal muscle.
Identifieur interne : 000618 ( Main/Exploration ); précédent : 000617; suivant : 000619Redox proteins are constitutively secreted by skeletal muscle.
Auteurs : Yasuko Manabe [Japon] ; Mayumi Takagi ; Mio Nakamura-Yamada ; Naoko Goto-Inoue ; Masato Taoka ; Toshiaki Isobe ; Nobuharu L. FujiiSource :
- The journal of physiological sciences : JPS [ 1880-6562 ] ; 2014.
Descripteurs français
- KwdFr :
- Animaux (MeSH), Exosomes (métabolisme), Fibres musculaires squelettiques (métabolisme), Glutarédoxines (métabolisme), Lignée cellulaire (MeSH), Muscles squelettiques (métabolisme), Oxydoréduction (MeSH), Peroxirédoxines (métabolisme), Souris (MeSH), Thiorédoxines (métabolisme), Vésicules de sécrétion (métabolisme).
- MESH :
English descriptors
- KwdEn :
- MESH :
- chemical , metabolism : Glutaredoxins, Peroxiredoxins, Thioredoxins.
- metabolism : Exosomes, Muscle Fibers, Skeletal, Muscle, Skeletal, Secretory Vesicles.
- Animals, Cell Line, Mice, Oxidation-Reduction.
Abstract
Myokines are skeletal muscle-derived hormones. In this study, using a C2C12 myotube contraction system, we sought to determine whether the skeletal muscle secreted thioredoxin (TRX) and related redox proteins. Redox proteins such as TRXs, peroxiredoxins, and glutaredoxins were detected in the C2C12 myotube culture medium in the absence of any stimulation. The amounts of TRXs, peroxiredoxins, and glutaredoxins secreted by the C2C12 myotubes were not affected by the contraction, unless the myotubes were injured. Because TRX-1 was known to be a secreted protein that lacks a signal peptide, we examined whether this protein was secreted via exosome vesicles. The results indicated that TRX-1 was not secreted via exosome vesicles. We concluded that TRX-1 and related redox proteins are myokines that are constitutively secreted by the skeletal muscle cells. Although the mechanism of TRX-1 secretion remains unclear, our findings suggest that the skeletal muscle is an endocrine organ and the redox proteins that are constitutively secreted from the skeletal muscle may exert antioxidant and systemic health-promoting effects.
DOI: 10.1007/s12576-014-0334-7
PubMed: 25205643
Affiliations:
Links toward previous steps (curation, corpus...)
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Fujii</name></author></analytic><series><title level="j">The journal of physiological sciences : JPS</title><idno type="eISSN">1880-6562</idno><imprint><date when="2014" type="published">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals (MeSH)</term><term>Cell Line (MeSH)</term><term>Exosomes (metabolism)</term><term>Glutaredoxins (metabolism)</term><term>Mice (MeSH)</term><term>Muscle Fibers, Skeletal (metabolism)</term><term>Muscle, Skeletal (metabolism)</term><term>Oxidation-Reduction (MeSH)</term><term>Peroxiredoxins (metabolism)</term><term>Secretory Vesicles (metabolism)</term><term>Thioredoxins (metabolism)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Animaux (MeSH)</term><term>Exosomes (métabolisme)</term><term>Fibres musculaires squelettiques (métabolisme)</term><term>Glutarédoxines (métabolisme)</term><term>Lignée cellulaire (MeSH)</term><term>Muscles squelettiques (métabolisme)</term><term>Oxydoréduction (MeSH)</term><term>Peroxirédoxines (métabolisme)</term><term>Souris (MeSH)</term><term>Thiorédoxines (métabolisme)</term><term>Vésicules de sécrétion (métabolisme)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Glutaredoxins</term><term>Peroxiredoxins</term><term>Thioredoxins</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Exosomes</term><term>Muscle Fibers, Skeletal</term><term>Muscle, Skeletal</term><term>Secretory Vesicles</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Exosomes</term><term>Fibres musculaires squelettiques</term><term>Glutarédoxines</term><term>Muscles squelettiques</term><term>Peroxirédoxines</term><term>Thiorédoxines</term><term>Vésicules de sécrétion</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Cell Line</term><term>Mice</term><term>Oxidation-Reduction</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Lignée cellulaire</term><term>Oxydoréduction</term><term>Souris</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Myokines are skeletal muscle-derived hormones. In this study, using a C2C12 myotube contraction system, we sought to determine whether the skeletal muscle secreted thioredoxin (TRX) and related redox proteins. Redox proteins such as TRXs, peroxiredoxins, and glutaredoxins were detected in the C2C12 myotube culture medium in the absence of any stimulation. The amounts of TRXs, peroxiredoxins, and glutaredoxins secreted by the C2C12 myotubes were not affected by the contraction, unless the myotubes were injured. Because TRX-1 was known to be a secreted protein that lacks a signal peptide, we examined whether this protein was secreted via exosome vesicles. The results indicated that TRX-1 was not secreted via exosome vesicles. We concluded that TRX-1 and related redox proteins are myokines that are constitutively secreted by the skeletal muscle cells. Although the mechanism of TRX-1 secretion remains unclear, our findings suggest that the skeletal muscle is an endocrine organ and the redox proteins that are constitutively secreted from the skeletal muscle may exert antioxidant and systemic health-promoting effects. </div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">25205643</PMID><DateCompleted><Year>2015</Year><Month>06</Month><Day>25</Day></DateCompleted><DateRevised><Year>2018</Year><Month>11</Month><Day>13</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1880-6562</ISSN><JournalIssue CitedMedium="Internet"><Volume>64</Volume><Issue>6</Issue><PubDate><Year>2014</Year><Month>Nov</Month></PubDate></JournalIssue><Title>The journal of physiological sciences : JPS</Title><ISOAbbreviation>J Physiol Sci</ISOAbbreviation></Journal><ArticleTitle>Redox proteins are constitutively secreted by skeletal muscle.</ArticleTitle><Pagination><MedlinePgn>401-9</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1007/s12576-014-0334-7</ELocationID><Abstract><AbstractText>Myokines are skeletal muscle-derived hormones. In this study, using a C2C12 myotube contraction system, we sought to determine whether the skeletal muscle secreted thioredoxin (TRX) and related redox proteins. Redox proteins such as TRXs, peroxiredoxins, and glutaredoxins were detected in the C2C12 myotube culture medium in the absence of any stimulation. The amounts of TRXs, peroxiredoxins, and glutaredoxins secreted by the C2C12 myotubes were not affected by the contraction, unless the myotubes were injured. Because TRX-1 was known to be a secreted protein that lacks a signal peptide, we examined whether this protein was secreted via exosome vesicles. The results indicated that TRX-1 was not secreted via exosome vesicles. We concluded that TRX-1 and related redox proteins are myokines that are constitutively secreted by the skeletal muscle cells. Although the mechanism of TRX-1 secretion remains unclear, our findings suggest that the skeletal muscle is an endocrine organ and the redox proteins that are constitutively secreted from the skeletal muscle may exert antioxidant and systemic health-promoting effects. </AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Manabe</LastName><ForeName>Yasuko</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>Department of Health Promotion Sciences, Graduate School of Human Health Sciences, Tokyo Metropolitan University, 1-1 Minami-Osawa, Hachioji, 192-0397, Japan.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Takagi</LastName><ForeName>Mayumi</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>Nakamura-Yamada</LastName><ForeName>Mio</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>Goto-Inoue</LastName><ForeName>Naoko</ForeName><Initials>N</Initials></Author><Author ValidYN="Y"><LastName>Taoka</LastName><ForeName>Masato</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>Isobe</LastName><ForeName>Toshiaki</ForeName><Initials>T</Initials></Author><Author ValidYN="Y"><LastName>Fujii</LastName><ForeName>Nobuharu L</ForeName><Initials>NL</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2014</Year><Month>09</Month><Day>10</Day></ArticleDate></Article><MedlineJournalInfo><Country>Japan</Country><MedlineTA>J Physiol Sci</MedlineTA><NlmUniqueID>101262417</NlmUniqueID><ISSNLinking>1880-6546</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D054477">Glutaredoxins</NameOfSubstance></Chemical><Chemical><RegistryNumber>52500-60-4</RegistryNumber><NameOfSubstance UI="D013879">Thioredoxins</NameOfSubstance></Chemical><Chemical><RegistryNumber>EC 1.11.1.15</RegistryNumber><NameOfSubstance UI="D054464">Peroxiredoxins</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002460" MajorTopicYN="N">Cell Line</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D055354" MajorTopicYN="N">Exosomes</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D054477" MajorTopicYN="N">Glutaredoxins</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D051379" 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2;280(48):40310-8</Citation><ArticleIdList><ArticleId IdType="pubmed">16207716</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Rev Endocrinol. 2012 Apr 03;8(8):457-65</Citation><ArticleIdList><ArticleId IdType="pubmed">22473333</ArticleId></ArticleIdList></Reference><Reference><Citation>Free Radic Res. 2001 Jul;35(1):23-30</Citation><ArticleIdList><ArticleId IdType="pubmed">11697114</ArticleId></ArticleIdList></Reference><Reference><Citation>Cardiovasc Res. 2010 Sep 1;87(4):628-35</Citation><ArticleIdList><ArticleId IdType="pubmed">20489058</ArticleId></ArticleIdList></Reference><Reference><Citation>J Mol Biol. 1998 Jul 3;280(1):85-102</Citation><ArticleIdList><ArticleId IdType="pubmed">9653033</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Rev Cancer. 2006 Oct;6(10):764-75</Citation><ArticleIdList><ArticleId IdType="pubmed">16990854</ArticleId></ArticleIdList></Reference><Reference><Citation>Diabetes. 2006 Oct;55(10 ):2688-97</Citation><ArticleIdList><ArticleId IdType="pubmed">17003332</ArticleId></ArticleIdList></Reference><Reference><Citation>Diabetes. 2002 Dec;51(12):3391-9</Citation><ArticleIdList><ArticleId IdType="pubmed">12453891</ArticleId></ArticleIdList></Reference><Reference><Citation>Diabetes. 2008 Dec;57(12):3211-21</Citation><ArticleIdList><ArticleId IdType="pubmed">18796617</ArticleId></ArticleIdList></Reference><Reference><Citation>J Exp Med. 1999 Jun 7;189(11):1783-9</Citation><ArticleIdList><ArticleId IdType="pubmed">10359582</ArticleId></ArticleIdList></Reference><Reference><Citation>Biochem Biophys Res Commun. 2014 Feb 21;444(4):496-501</Citation><ArticleIdList><ArticleId IdType="pubmed">24472542</ArticleId></ArticleIdList></Reference><Reference><Citation>J Appl Physiol (1985). 2001 Aug;91(2):534-51</Citation><ArticleIdList><ArticleId IdType="pubmed">11457764</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Immunol. 2002 Feb;38(10):793-9</Citation><ArticleIdList><ArticleId IdType="pubmed">11841839</ArticleId></ArticleIdList></Reference><Reference><Citation>Oxid Med Cell Longev. 2012;2012:756132</Citation><ArticleIdList><ArticleId IdType="pubmed">22701757</ArticleId></ArticleIdList></Reference><Reference><Citation>Eur J Appl Physiol. 2013 May;113(5):1117-26</Citation><ArticleIdList><ArticleId IdType="pubmed">23108583</ArticleId></ArticleIdList></Reference><Reference><Citation>Immunol Lett. 1994 Sep;42(1-2):75-80</Citation><ArticleIdList><ArticleId IdType="pubmed">7829134</ArticleId></ArticleIdList></Reference><Reference><Citation>Semin Immunol. 2013 Dec 15;25(6):425-9</Citation><ArticleIdList><ArticleId IdType="pubmed">24201029</ArticleId></ArticleIdList></Reference><Reference><Citation>Physiol Rev. 2008 Oct;88(4):1243-76</Citation><ArticleIdList><ArticleId IdType="pubmed">18923182</ArticleId></ArticleIdList></Reference><Reference><Citation>Free Radic Biol Med. 2007 Oct 1;43(7):1061-75</Citation><ArticleIdList><ArticleId IdType="pubmed">17761302</ArticleId></ArticleIdList></Reference><Reference><Citation>Biochem Biophys Res Commun. 2003 Nov 14;311(2):372-9</Citation><ArticleIdList><ArticleId IdType="pubmed">14592424</ArticleId></ArticleIdList></Reference><Reference><Citation>Free Radic Biol Med. 2008 Jan 15;44(2):126-31</Citation><ArticleIdList><ArticleId IdType="pubmed">18191748</ArticleId></ArticleIdList></Reference><Reference><Citation>Exp Mol Pathol. 1983 Jun;38(3):380-8</Citation><ArticleIdList><ArticleId IdType="pubmed">6852210</ArticleId></ArticleIdList></Reference><Reference><Citation>Oncol Res. 1994;6(10-11):539-44</Citation><ArticleIdList><ArticleId IdType="pubmed">7620223</ArticleId></ArticleIdList></Reference><Reference><Citation>Nature. 2012 Jan 11;481(7382):463-8</Citation><ArticleIdList><ArticleId IdType="pubmed">22237023</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Rev Mol Cell Biol. 2009 Feb;10(2):148-55</Citation><ArticleIdList><ArticleId IdType="pubmed">19122676</ArticleId></ArticleIdList></Reference><Reference><Citation>J Clin Invest. 1996 Dec 1;98(11):2469-77</Citation><ArticleIdList><ArticleId IdType="pubmed">8958209</ArticleId></ArticleIdList></Reference><Reference><Citation>Gen Physiol Biophys. 2004 Jun;23(2):241-9</Citation><ArticleIdList><ArticleId IdType="pubmed">15696862</ArticleId></ArticleIdList></Reference><Reference><Citation>Lymphokine Cytokine Res. 1992 Oct;11(5):201-7</Citation><ArticleIdList><ArticleId IdType="pubmed">1334710</ArticleId></ArticleIdList></Reference><Reference><Citation>Stem Cells. 2012 Oct;30(10):2271-82</Citation><ArticleIdList><ArticleId IdType="pubmed">22865667</ArticleId></ArticleIdList></Reference><Reference><Citation>Am J Physiol Endocrinol Metab. 2005 Aug;289(2):E251-7</Citation><ArticleIdList><ArticleId IdType="pubmed">15755769</ArticleId></ArticleIdList></Reference><Reference><Citation>Am J Physiol Endocrinol Metab. 2008 Nov;295(5):E1191-204</Citation><ArticleIdList><ArticleId IdType="pubmed">18780777</ArticleId></ArticleIdList></Reference><Reference><Citation>Life Sci. 2003 Feb 21;72(14):1627-33</Citation><ArticleIdList><ArticleId IdType="pubmed">12551751</ArticleId></ArticleIdList></Reference><Reference><Citation>Cancer Res. 1995 Feb 1;55(3):675-80</Citation><ArticleIdList><ArticleId IdType="pubmed">7834639</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Protoc. 2006;1(1):16-22</Citation><ArticleIdList><ArticleId IdType="pubmed">17406207</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS One. 2012;7(12):e52592</Citation><ArticleIdList><ArticleId IdType="pubmed">23300713</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Neurobiol. 2003 Apr;27(2):163-76</Citation><ArticleIdList><ArticleId IdType="pubmed">12777686</ArticleId></ArticleIdList></Reference><Reference><Citation>FASEB J. 1996 Mar;10(4):502-9</Citation><ArticleIdList><ArticleId IdType="pubmed">8647349</ArticleId></ArticleIdList></Reference><Reference><Citation>Exp Cell Res. 2010 Jul 15;316(12):1977-84</Citation><ArticleIdList><ArticleId IdType="pubmed">20399774</ArticleId></ArticleIdList></Reference><Reference><Citation>J Appl Physiol (1985). 2007 Sep;103(3):1093-8</Citation><ArticleIdList><ArticleId IdType="pubmed">17347387</ArticleId></ArticleIdList></Reference><Reference><Citation>EMBO J. 2007 Jul 11;26(13):3086-97</Citation><ArticleIdList><ArticleId IdType="pubmed">17557078</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 1992 Dec 5;267(34):24161-4</Citation><ArticleIdList><ArticleId IdType="pubmed">1332947</ArticleId></ArticleIdList></Reference></ReferenceList></PubmedData></pubmed><affiliations><list><country><li>Japon</li></country></list><tree><noCountry><name sortKey="Fujii, Nobuharu L" sort="Fujii, Nobuharu L" uniqKey="Fujii N" first="Nobuharu L" last="Fujii">Nobuharu L. Fujii</name><name sortKey="Goto Inoue, Naoko" sort="Goto Inoue, Naoko" uniqKey="Goto Inoue N" first="Naoko" last="Goto-Inoue">Naoko Goto-Inoue</name><name sortKey="Isobe, Toshiaki" sort="Isobe, Toshiaki" uniqKey="Isobe T" first="Toshiaki" last="Isobe">Toshiaki Isobe</name><name sortKey="Nakamura Yamada, Mio" sort="Nakamura Yamada, Mio" uniqKey="Nakamura Yamada M" first="Mio" last="Nakamura-Yamada">Mio Nakamura-Yamada</name><name sortKey="Takagi, Mayumi" sort="Takagi, Mayumi" uniqKey="Takagi M" first="Mayumi" last="Takagi">Mayumi Takagi</name><name sortKey="Taoka, Masato" sort="Taoka, Masato" uniqKey="Taoka M" first="Masato" last="Taoka">Masato Taoka</name></noCountry><country name="Japon"><noRegion><name sortKey="Manabe, Yasuko" sort="Manabe, Yasuko" uniqKey="Manabe Y" first="Yasuko" last="Manabe">Yasuko Manabe</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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